Differin Gel Acne Treatment contains adapalene an Rx-strength acne-fighting retinoid that helps clear breakouts where they start (works deep into pores in 5 minutes) helps prevents new acne from forming and as a result can restore skin?s overall tone and texture. Adapalene is the first over-the-counter active ingredient for acne in more than 30 years. It clears acne with the power of an Rx without the prescription prevents breakouts blackheads whiteheads blemishes and clogged pores and can be used to effectively treat acne or maskne caused by wearing face masks or facial coverings. When used as directed you could start to see results in as little as 1 week and when used every single day Differin Gel can help reduce up to 87% of acne in just 12 weeks (Cunliffe et al 1998 Galderma Laboratories).