Doctor?s Best SAM-e helps replenish your SAM-e levels and promote a healthy mood.* SAM-e (S-Adenosyl-L-Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e leaving you feeling unbalanced and moody. Supplementing with SAM-e Soloesse? Italian SAM-e is processed to yield the highest available percentage of the active pure S S form which helps mediate biochemical activity in the human body.* SAM-e and Mood and Cognitive Function SAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body?s antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.* SAM-e and Joint Function In clinical trials SAM-e has been shown to help increase joint comfort and mobility by promoting the sy