Since 1947 Extra Strength Shellfish-Free Promotes Health Joints Supports Comfortable Movement Non-GMO Certified Gluten-Free Wheat & Dairy Free Dietary Supplement Regenasure? Glucosamine Made with BioCell Collagen OptiMSM? Glucosamine supports mobility range of motion and flexibility. It helps ease occasional joint stress due to exercise or physical activity. Chondroitin supports cartilage and joint function. MSM (Methylsulfonylmethane) provides a natural bioavailable source of sulfur and promotes joint comfort. MSM works synergistically to support the benefits of glucosamine and chondroitin. This formulation also provides Hyaluronic Acid.